Payment/claims data was never fit for the purpose of understanding patients’ use of medicines, yet we still rely on it for critical strategic decisions - there is a better way.
Written by: Jeff Wandzura, RPh, CEO of KEEP
During my time as a pharmacist, I realized the core function of pharmacy fill (payment/claims) data was to solve an accounting problem, yet we’re trying to repurpose it to inform critical strategic and clinical decisions around real world use of medicines. This simplistic and surface level view has left a void in our ability to understand, support and optimize the treatment journey.
Out of convenience, and constrained by data availability, the healthcare community has relied on a significant assumption that a patient who receives and has ‘access’ to their therapy is in fact using it properly on a day-by-day and dose-by-dose basis. However, our line of sight to the medication experience has traditionally stopped once a medication leaves the pharmacy.
As someone who spent many years as a pharmacist, I know first-hand this is often far from reality, and can cause us to miss the plot line, especially with more complex, specialty medications being shifted from the hospital/clinic setting to now being managed to the new front-line of care; the home.

Mind The (Data) Gap
Imagine driving a car and you’re forced to close your eyes for 30 seconds at a time. At that point, you can look at your rearview mirror to see where you’ve driven and take some vague guesses on the road ahead based on what you observe. You repeat this cycle over and over, till one time the music stops after you veer off course. No, of course you wouldn’t, it would be reckless for you and others – yet we do this with our customers, physicians and patients.
That’s the reality when you’re relying on claims data – you get a snapshot in time with 30 days blacked out and you’re blind to the information in between those data points from the financial claims data being repurposed to measure adherence. Then, the dated data stream stops. Did the patient switch to another therapy, stop treatment altogether or was there another issue? After that, you wait another 30 day cycle to see if the patient was simply late with their refill.
The New Front Line of Care

The New Front Line of Care
The data we currently have access to stops once a medication leaves the pharmacy counter, but this is where the therapeutic journey starts; not ends. This wasn’t as significant of a problem when specialty medications were administered in the clinic or hospital, and full line of sight to administration was realized, but the majority of approved and pipeline specialty medications are now being shifted to the home, which provides both convenience and downstream risks.
Different dynamics are at play in the home, and both the measurement and support structures in place need to adapt if we want to optimize the outcomes and treatment experience for patients and their families, with clear benefits for health systems and biopharma companies. The first step in this process is to gain a deeper understanding of the treatment journey by gaining visibility to the dose-by-dose experience in the home.


Why Does it Matter? The Short-Term & Long-Term Impact
As we know, even the best medications only work when they’re taken. When we’re forced to look into the rear-view mirror, with significant gaps in visibility, we can’t proactively identify and help patients who need support, let alone measure which interventions are working.
Without having line of sight to data beyond the pharmacy, programs have been created that try to close the gap by layering in expensive check-in calls through expensive and inefficient patient support programs, treating every patient the same, independent of the status of their medication adherence.
Ultimately, we see patients struggling to manage medications, dropping off therapy prematurely (due to avoidable reasons), inefficient use of resources to engage patients and our partners and prescribers flying blind to ways they can help by leveraging personalized interventions that adapt to the patients’ needs based on real-time data.
Shifting From Retrospective to Proactive Care
This is why, in building KEEP, we are so passionate about delivering solutions that can answer key questions to help close the data gap from the pharmacy counter (claims) to true utilization in the home, plus redefine how to empower patients and partners to get the most from their medication.
I’m happy to expand more on exactly how we do this, but as a teaser, here are some questions and insights we’re starting to uncover that claims data can’t tell you:
- What dose of the week is at greatest risk of being missed? For what patient segment?
- Is there a leading indicator to a patient discontinuing treatment?
- Are patients intentionally skipping (medical reason) or missing (forgetting) doses?
- Is a specific patient support tactic actually moving the needle?
- Does the location of medication storage impact adherence or persistence?
- Does time of day impact their outcomes with medication not following them out of the home?
The intriguing aspect to when we have line of sight to a more granular view of the patient journey is we do know what we don’t know, and KEEP helps to close that gap.
Clinical trials have understood this confounding factor to treatment outcomes, leveraging analog calls and other means to close this data gap, and with new technology, like KEEP, democratizing access to treatment enablers at scale it’s time the industry moves from an antiquated adherence measure borne out of necessity and convenience, due to limited data availability, to one that enables the optimal understanding and support of patients. Our technology and data capabilities have since progressed, but our methods haven’t.
In this way, new insights are continually generated that help uncover new strategies that advance the way personalized care experiences are realized, improve outcomes and deliver success for all stakeholders.
If you want to learn more about how a dose-by-dose approach to measuring adherence can be implemented, please reach out.